CPSP, previously known as Dejerine-Roussy syndrome and thalamic pain syndrome, is a feared complication of cerebrovascular accidents and has been. Stroke and pain can sometimes result in Dejerine-Roussy syndrome. Available treatments include antidepressants, anticonvulsants, and. Due to the high clinical variability in presentation of Déjerine-Roussy syndrome, it is impossible to predict which patients with a thalamic stroke will develop pain.

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Pain can fluctuate during the day and can be affected by several factors including touch, emotions such as stress, certain movements or overall level of activity, and temperature changes, especially cold temperatures. Support Radiopaedia and see fewer ads.

Introduction Central post-stroke pain is cejerine rare central neuropathic pain also known as Dejerine Roussy syndrome, and thalamic pain syndrome occurs after infarction of the ventroposterolateral thalamus. This page was last edited on 6 Octoberat Although the thalamus is the location of the lesion implicated synerome this syndrome, central post-stroke pain can also occur due to lesions at any level of the spinothalamic pathwaysuch as in patients with the lateral medullary syndrome or with cortical lesions 2,7.

In severe cases, this can include pain caused by a fejerine breeze, the weight of a blanket, or even the clothes a person is wearing. For information about clinical trials sponsored by private sources, contact: Central post-stroke pain is often split into three components.

Repetitive transcranial magnetic stimulation r TMS: It is now accepted that Dejerine—Roussy syndrome is a condition developed due to lesions interfering with the sensory process, which triggered the start of pharmaceutical and stimulation treatment research.


Recent advances in the field of spinal cord injury suggest that removal of an injured segment of the spinal cord, wherever feasible, accompanied by vertebrectomy or multiple discectomies might benefit both motor and sensory recovery.

Jahngir 1 ; Adnan I. Central pain syndrome can be broken down into central pain of brain or brainstem origin or central pain of spinal cord origin.

Dejerine—Roussy syndrome is most commonly preceded by numbness in the affected side. More recently, electrical stimulation of the brain and spinal cord and caloric stimulation have been explored as treatments. Symptoms are generally not treatable with ordinary analgesics. Overall results to relieve pain in the patients are variable but encouraging.

There is a need for a new, less expensive, less invasive form of treatment, two of which are postulated below. It is found to be effective, but more trials are needed.

The imbalance in sensation characterized by Dejerine—Roussy syndrome can be argued through a model addressing a system of inputs and outputs that the brain must constantly process throughout life, suggesting latent plasticity. StatPearls Publishing; Jan.

In published, peer-reviewed scientific articles by Dr. Extradurally means that the paddle is placed on the dura mater, the outermost layer of the membranes meninges that line the brain and spinal cord. Please review our privacy policy. Some individuals with central post-stroke pain may experience painful symptoms on one roussu of the body from head to foot ; other notable, accompanying symptoms include loss of sensation hemihypesthesiapartial or complete muscle weakness hemiparesis, hemiplegiaandon occasion, abnormal, involuntary, irregular jerky motions and slow, writhing movements hemichoreoathetosis.

The name Dejerine—Roussy syndrome was coined after their deaths. For the last thirty years, experience has accumulated on the semiology of lesions deerine the nuclei of convergence.


Antiplatelet medications especially cilostazol may have roussu role in the treatment of central post-stroke pain. Symptoms of peripheral neuropathic pain e.

Many chemical medications have been used for a broad range of neuropathic pain including Dejerine—Roussy syndrome.

Since then, the thalamic syndrome has not ceased to arouse the attention of neurologists, who have developed four major themes: Central sensitization is the increased synaptic efficacy of the central afferent neurons leads to spontaneous pain or nociception on suboptimal stimulus.

Encephalomyelitis Acute disseminated Myalgic Meningoencephalitis.

Dejerine–Roussy syndrome – Wikipedia

Two drugs, amitriptyline and lamotrigine, have proven beneficial in controlled trials, especially for individuals with central pain of brain origin. Dejerine—Roussy syndrome has also been referred to as: Prognosis Central post-stroke pain is a persistent pain and may be life-long.

The insular cortex is often lesioned by a stroke. Central pain syndrome can be limited to a specific area of the body such as the hands or feet or may be widespread over a large portion of deejrine body.

Dejerine–Roussy syndrome

The quality of pain foussy and is often described as pricking, aching, lancinating, shooting, squeezing, freezing, lacerating, electrical, cold, numb, swollen, cutting, dull, and throbbing. Central pain syndrome is a neurological disorder caused by damage to the sensory pathways of the central nervous system CNS. Loading Stack – 0 images remaining. Brain herniation Reye’s Hepatic encephalopathy Toxic encephalopathy Hashimoto’s encephalopathy.